Mouse Genome Informatics
hm
    Clrn1tm2.1Kuna/Clrn1tm2.1Kuna
involves: 129 * BALB/cJ * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
hearing/vestibular/ear
• disrupted integrity that is not as profound at P18 or P21 as in Clrn1tm1.1Kuna homozygotes
• however, tip links are normal
• not as profound at P18 or P21 as in Clrn1tm1.1Kuna homozygotes
• early onset hearing loss that progresses to deafness by weaning

nervous system
• disrupted integrity that is not as profound at P18 or P21 as in Clrn1tm1.1Kuna homozygotes
• however, tip links are normal

Mouse Models of Human Disease
OMIM IDRef(s)
Usher Syndrome, Type IIIA; USH3A 276902 J:186316