Analysis Tools
mortality/aging
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• nearly all mice die within the first 24 hours after birth
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nervous system
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• at E18.5, neuronal stem cells exhibit altered shape at the apical border compared with control cells
• cultured neural stem cells fail to form primary and secondary neurospheres unlike control cells
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• of neural stem cells in vitro and in vivo as determined by marker expression
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• at E18.5, neural stem cell proliferation is reduced with prolonged cell cycle timing and increased probability of exiting the cell cycle compared with control cells
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• hypocellular at E18.5 and P0
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• disrupted pseudo-stratified architecture at E18.5
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• at E18.5 and P0
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• at E18.5 and P0
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cellular
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• at E18.5, neural stem cell proliferation is reduced with prolonged cell cycle timing and increased probability of exiting the cell cycle compared with control cells
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• at E18.5, neuronal stem cells exhibit altered shape at the apical border compared with control cells
• cultured neural stem cells fail to form primary and secondary neurospheres unlike control cells
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• of neural stem cells in vitro and in vivo as determined by marker expression
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• at E18.5, neural stem cell proliferation is reduced with prolonged cell cycle timing and increased probability of exiting the cell cycle compared with control cells
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