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Phenotypes Associated with This Genotype
Genotype
MGI:5428448
Allelic
Composition
Snap25Bdr/Snap25+
Genetic
Background
involves: BALB/cAnNCrl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Snap25Bdr mutation (2 available); any Snap25 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• mice exhibit normal activity levels, startle response amplitude, anxiety-related behavior and spatial learning
• at 4 weeks

endocrine/exocrine glands
• basal and stimulated
• defective vesicle turnover and exocytosis after depletion of intermediate and readily releasable pools
• basal and stimulated

homeostasis/metabolism
• basal and stimulated
• basal and stimulated

nervous system
• reduced frequency but not amplitude
• sponataneous and evoked

taste/olfaction
N
• mice exhibit normal olfaction

Mouse Models of Human Disease
OMIM ID Ref(s)
Schizophrenia; SCZD 181500 J:119733


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory