Mouse Genome Informatics
ht
    Gata4tm1Grg/Gata4+
involves: 129 * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Atrial septal defects and semilunar valve stenosis in Gata4tm1Grg/Gata4+ mice

cardiovascular system
• in 4 of 12 mutants
• increase in the frequency of mice with intermittent shunting of blood between the atria
• thickened aortic valve leaflets
• in 2 of 12 mutants
• thickened pulmonary valve leaflets

cellular

muscle

Mouse Models of Human Disease
OMIM IDRef(s)
Atrial Septal Defect 2; ASD2 607941 J:185124