About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5427103
Allelic
Composition		 Tmc1tm1.1Ajg/Tmc1+
Tmc2tm1.1Ajg/Tmc2tm1.1Ajg
Genetic
Background		 B6.129-Tmc2tm1.1Ajg Tmc1tm1.1Ajg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tmc1tm1.1Ajg mutation (1 available); any Tmc1 mutation (60 available)
Tmc2tm1.1Ajg mutation (1 available); any Tmc2 mutation (42 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal vestibuloocular dark reflex ( J:184419 )
• reduced acceleration gain values at 2-3 months of age compared to wild-type controls but increased compared to double homozygous mice

hearing/vestibular/ear
abnormal vestibuloocular dark reflex ( J:184419 )
• reduced acceleration gain values at 2-3 months of age compared to wild-type controls but increased compared to double homozygous mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory