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Phenotypes Associated with This Genotype
Genotype
MGI:5317804
Allelic
Composition
Pld2tm1.1Mjow/Pld2tm1.1Mjow
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pld2tm1.1Mjow mutation (0 available); any Pld2 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• neutrophils exhibit a small reduction in basal phosphatidic acid compared with wild-type mice
• however, production of phospatidic acids from neutrophils stimulated with PMA or fMLP is normal and production of reactive oxygen species is normal

hematopoietic system
• neutrophils exhibit a small reduction in basal phosphatidic acid compared with wild-type mice
• however, production of phospatidic acids from neutrophils stimulated with PMA or fMLP is normal and production of reactive oxygen species is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory