mortality/aging
• mice do not survive beyond E12.5
|
limbs/digits/tail
• lack of calcification at E12.5
|
• broad at E12.5 relative to E11.5 wild-type limb buds, suggesting polydactyly
|
• delayed at E11.5 and E12.5
|
embryo
• broad at E12.5 relative to E11.5 wild-type limb buds, suggesting polydactyly
|
vision/eye
anophthalmia
(
J:181886
)
• absent eyes at E11.5 to E13.5
|
cardiovascular system
• at E11.5 to E13.5
|
craniofacial
cleft palate
(
J:181886
)
• at E11.5 to E13.5
|
nervous system
exencephaly
(
J:181886
)
• at E11.5 to E13.5
|
homeostasis/metabolism
• at E11.5 to E13.5
|
digestive/alimentary system
cleft palate
(
J:181886
)
• at E11.5 to E13.5
|
growth/size/body
cleft palate
(
J:181886
)
• at E11.5 to E13.5
|