Analysis Tools
immune system
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• IgE switching is abolished following exposure to ovalbumin
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• following exposure to ovalbumin, type 2 responses are reduced (pulmonary resistance, numbers of eosinophils and lymphocytes in bronchoalveolar lavage fluid and IgE switching) compared with wild-type mice
• mice exposed to Leishmania exhibit decreased IgE, decreased IgG1 and increased IgG2b compared with wild-type mice
• however, ovalbumin-exposed mice exhibit normal peribronchial and perivascular inflammatory infiltrates and mucus hypersecretion typical of allergic inflammation and normal footpad swelling and Leishmania-exposed mice exhibit normal parasite titer in response to
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• following exposure to ovalbumin
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• in response to Leishmania exposure
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• in response to Leishmania exposure
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• in Th2 polarized CD4+ T cells
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• in Th2 polarized CD4+ T cells
• in restimulated T cells in the draining popliteal lymph nodes of mice exposed to Leishmania
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• mice exposed to Leishmania exhibit decreased IgE, decreased IgG1 and increased IgG2b compared with wild-type mice
• however, mice exhibit normal footpad swelling and parasite titer
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respiratory system
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• following exposure to ovalbumin
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hematopoietic system
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• IgE switching is abolished following exposure to ovalbumin
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• following exposure to ovalbumin
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• in response to Leishmania exposure
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• in response to Leishmania exposure
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