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Phenotypes Associated with This Genotype
Genotype
MGI:5312334
Allelic
Composition
Dnaaf4b2b811.1Clo/Dnaaf4b2b811.1Clo
Genetic
Background
C57BL/6J-Dnaaf4b2b811.1Clo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dnaaf4b2b811.1Clo mutation (1 available); any Dnaaf4 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype

Mutant 811-058-LB exhibits inverted outflow that is diagnosed with overriding aorta by EFIC imaging

cardiovascular system
• in some mice
• left-sided in some mice
• in some mice with right atrial isomerism, muscular and atrioventricular septal defect
• in some mice with double outlet right ventricle, muscular and atrioventricular septal defect
• in some mice
• in some mice with right atrial isomerism and double outlet right ventricle
• in some mice with double outlet right ventricle, right atrial isomerism and atrioventricular septal defect (J:205312)
• in some mice with double outlet right ventricle, right atrial isomerism and atrioventricular septal defect
• biventricular hypertrophy

growth/size/body
• biventricular hypertrophy
• in some mice with double outlet right ventricle, muscular and atrioventricular septal defect
• in some mice
• in some mice
• in some mice (J:205312)

skeleton

digestive/alimentary system
• in some mice

endocrine/exocrine glands
• left-sided pancreas in some mice

hematopoietic system
• left-sided spleen in some mice

respiratory system
• immotile cilia
• in some mice

immune system
• left-sided spleen in some mice

cellular
• immotile cilia

mortality/aging
• some mice with congenital heart defects die at birth
• some mice with congenital heart defects die prenatally

nervous system

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
Robinow syndrome DOID:0060254 OMIM:PS268310
J:175213


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/27/2022
MGI 6.21
The Jackson Laboratory