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Phenotypes Associated with This Genotype
Genotype
MGI:5308797
Allelic
Composition		 Mir34atm1.1Lhe/Mir34atm1.1Lhe
Pou5f1tm2Jae/Pou5f1+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir34atm1.1Lhe mutation (1 available); any Mir34a mutation (9 available)
Pou5f1tm2Jae mutation (1 available); any Pou5f1 mutation (82 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell physiology ( J:180692 )
• induced mouse embryonic fibroblasts exhibit a greater than 4-fold increase in reprogramming efficiency and generation of induced pluripotent stem cell compared with wild-type and Mir34atm1.1Ghan cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory