Phenotypes for Nrn1 Tg(Thy1-EGFP)SJrs MGI:5307920 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nrn1^tm1.2Ndiv/Nrn1^tm1.2Ndiv Tg(Thy1-EGFP)SJrs/0
Genetic Background	involves: C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrn1^tm1.2Ndiv mutation (1 available); any Nrn1 mutation (18 available)
Tg(Thy1-EGFP)SJrs mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

abnormal CNS synapse formation ( J:178970 )

• the percentage of dynamic events (spine gain or loss from neocortical neurons) that persist are significantly higher compared to wild-type mice

• the percentage of dynamic-persistent events that favor spine loss relative to dynamic-persistent events that favor spine gain is increased compared to wild-type controls suggesting a decrease in spine stabilization

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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