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Phenotypes Associated with This Genotype
Genotype
MGI:5302546
Allelic
Composition
Mecp2tm1.1Meg/Y
Genetic
Background
B6.129-Mecp2tm1.1Meg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mecp2tm1.1Meg mutation (0 available); any Mecp2 mutation (38 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• male mice are fertile

behavior/neurological
N
• mice exhibit normal anxiety-related and motor behaviors, social approach, and spatial learning and memory
• mice spend equal time investigating a novel objects or mouse as a familiar object or mouse unlike wild-type mice
• mice spend equal time investigating a novel objects as a familiar object unlike wild-type mice

nervous system
• cultured cortical neurons exhibit an increase in the average number of dendritic branches and increased dendritic complexity compared with wild-type cells


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory