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Phenotypes Associated with This Genotype
Genotype
MGI:5297352
Allelic
Composition		 Gab2tm3.1Thir/Gab2tm3.1Thir
Genetic
Background		 involves: 129T/SvJcl * C57BL/6Jcl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gab2tm3.1Thir mutation (1 available); any Gab2 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:178045 )
N
• bone marrow-derived mast cells exhibit normal Fcer1-induced cytokine production
decreased mast cell number ( J:178045 )
• in mucosal mast cells, but not skin mast cells

hematopoietic system
decreased mast cell number ( J:178045 )
• in mucosal mast cells, but not skin mast cells

cellular

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory