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Phenotypes Associated with This Genotype
Genotype
MGI:5292677
Allelic
Composition
Nr5a1tm1.1Hain/Nr5a1tm1.1Hain
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nr5a1tm1.1Hain mutation (0 available); any Nr5a1 mutation (30 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
• persistence of fetal X-zone

mortality/aging
N
• unlike null mice, mice are viable

reproductive system
• irregularly branched, thin cords are seen as early as E13.5
• dramatic reduction in testicular weight

homeostasis/metabolism
• decreased adrenal aldosterone levels
• elevated adrenal corticosterone level
• elevated testicular progesterone levels
• elevated testicular testosterone levels

endocrine/exocrine glands
• persistence of fetal X-zone
• significant but subtle decrease in weight
• irregularly branched, thin cords are seen as early as E13.5
• dramatic reduction in testicular weight


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory