Phenotypes Associated with This Genotype

Genotype
MGI:5291909

• Allelic Composition: Rbfox1^tm1.1Dblk/Rbfox1⁺; Tg(Nes-cre)1Kln/0
• Genetic Background: involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

increased susceptibility to xenobiotic induced morbidity/mortality ( J:176189 )

• in mice treated with kainic acid

nervous system

increased susceptibility to pharmacologically induced seizures ( J:176189 )

• increased incidence resulting in death in response to kainic acid treatment

behavior/neurological

increased susceptibility to pharmacologically induced seizures ( J:176189 )

• increased incidence resulting in death in response to kainic acid treatment

homeostasis/metabolism

increased susceptibility to xenobiotic induced morbidity/mortality ( J:176189 )

• in mice treated with kainic acid