Mouse Genome Informatics
ht
    Del(7Slx1b-Sept1)4Aam/+
involves: 129S7/SvEvBrd * C57BL/6N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• some mice die between birth and weaning

behavior/neurological
• mice exhibit higher distance traveled, time spent walking, and time spent lingering compared with control mice
• after habituation, mice exhibit a second burst of activity (walking and rearing) unlike control mice
• mice spend less time resting than control mice
• mice are more active in the dark and light phases compared with control mice
• mice exhibit a higher ratio of light to dark activity compared with control mice
• mice exhibit extremely stereotypic ceiling-climbing unlike control mice with some mice becoming trapped on the ceiling for extensive periods

nervous system
• in the posterior, lateral regions compared with Dp(7Slx1b-Sept1)5Aam mice
• in the lateral hypothalamus

growth/size/body
• prior to weaning but not as adults

Mouse Models of Human Disease
OMIM IDRef(s)
Autism 209850 J:176335