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Phenotypes Associated with This Genotype
Genotype
MGI:5291505
Allelic
Composition
Del(7Slx1b-Sept1)4Aam/+
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(7Slx1b-Sept1)4Aam mutation (1 available); any Del(7Slx1b-Sept1)4Aam mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• some mice die between birth and weaning

behavior/neurological
• mice exhibit higher distance traveled, time spent walking, and time spent lingering compared with control mice
• after habituation, mice exhibit a second burst of activity (walking and rearing) unlike control mice
• mice spend less time resting than control mice
• mice are more active in the dark and light phases compared with control mice
• mice exhibit a higher ratio of light to dark activity compared with control mice
• mice exhibit extremely stereotypic ceiling-climbing unlike control mice with some mice becoming trapped on the ceiling for extensive periods

nervous system
• in the posterior, lateral regions compared with Dp(7Slx1b-Sept1)5Aam mice
• in the lateral hypothalamus

growth/size/body
• prior to weaning but not as adults

Mouse Models of Human Disease
OMIM ID Ref(s)
Autism 209850 J:176335


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory