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Phenotypes Associated with This Genotype
Genotype
MGI:5288598
Allelic
Composition
Nrp1tm1.1Cruh/Nrp1tm1.1Cruh
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrp1tm1.1Cruh mutation (0 available); any Nrp1 mutation (47 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• significant increase in artery vein crossing points
• arteries are positioned anteriorly to veins in the crossing points

cardiovascular system
N
• unlike in null mice, embryonic vasculogenesis and angiogenesis are normal
• significant increase in artery vein crossing points
• arteries are positioned anteriorly to veins in the crossing points

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
retinal vein occlusion DOID:1727 J:176047


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory