About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5287721
Allelic
Composition
Gbatm2Ggb/Gbatm2Ggb
Psaptm1Suz/Psaptm1Suz
Genetic
Background
involves: 129P2/OlaHsd * 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gbatm2Ggb mutation (0 available); any Gba mutation (12 available)
Psaptm1Suz mutation (1 available); any Psap mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• degenerating neurons are seen in multiple brain regions in 12 week old mutants, including the substantia nigra and cortex as indicated by the presence of eosinophilic spheroids (J:174780)
• degenerative changes occur concomitantly with an accumulation of soluble and insoluble alpha-synuclein (J:174780)
• degenerating neurons are seen in multiple brain regions in 12 week old mutants, including the substantia nigra and cortex as indicated by the presence of eosinophilic spheroids (J:174780)
• degenerative changes occur concomitantly with an accumulation of soluble and insoluble alpha-synuclein (J:174780)


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/26/2016
MGI 6.02
The Jackson Laboratory