Mouse Genome Informatics
cx
    Gbatm2Ggb/Gbatm2Ggb
Psaptm1Suz/Psaptm1Suz

involves: 129P2/OlaHsd * 129S5/SvEvBrd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• degenerating neurons are seen in multiple brain regions in 12 week old mutants, including the substantia nigra and cortex as indicated by the presence of eosinophilic spheroids
• degenerative changes occur concomitantly with an accumulation of soluble and insoluble alpha-synuclein

Mouse Models of Human Disease
OMIM IDRef(s)
Gaucher Disease, Type I 230800 J:174780
Gaucher Disease, Type II 230900 J:174780
Gaucher Disease, Type III 231000 J:174780