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Phenotypes Associated with This Genotype
Genotype
MGI:5141744
Allelic
Composition
Tg(UPII-SV40T)2Xrw/0
Genetic
Background
involves: FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
renal/urinary system
• mutants succumb to bladder cancer at 3 months of age, developing patches of bladder carcinoma in situ (CIS)
• mutants also develop moderately differentiated transitional cell carcinoma (TCC) that invades into the detrusor muscle layer

neoplasm
• mutants succumb to bladder cancer at 3 months of age, developing patches of bladder carcinoma in situ (CIS)
• mutants also develop moderately differentiated transitional cell carcinoma (TCC) that invades into the detrusor muscle layer

Mouse Models of Human Disease
OMIM ID Ref(s)
Bladder Cancer 109800 J:56305


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
06/15/2016
MGI 6.04
The Jackson Laboratory