About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5086118
Allelic
Composition
Amelxtm1Kul/Amelxtm1Kul
Tg(AMELX*P70T)2Gibs/?
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Amelxtm1Kul mutation (1 available); any Amelx mutation (17 available)
Tg(AMELX*P70T)2Gibs mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
skeleton
• molar enamel has a hyperplastic intermedium cell layer exhibiting transition to tumor cells

neoplasm
• molar enamel has a hyperplastic intermedium cell layer exhibiting transition to tumor cells
• tumor is composed of benign, eosinophilic, polygonal-shaped cells with intercellular bridges
• calcification is not obvious in these tumors

craniofacial
• molar enamel has a hyperplastic intermedium cell layer exhibiting transition to tumor cells

growth/size/body
• molar enamel has a hyperplastic intermedium cell layer exhibiting transition to tumor cells

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amelogenesis imperfecta type 1E DOID:0110058 OMIM:301200
J:122914


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/21/2017
MGI 6.08
The Jackson Laboratory