About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5085876
Allelic
Composition		 Nlrp3tm1Flv/Nlrp3tm1Flv
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrp3tm1Flv mutation (1 available); any Nlrp3 mutation (61 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
digestive/alimentary system
decreased susceptibility to induced colitis ( J:173245 )
• dextran sodium sulfate (DSS)-treated mice housed with wild-type mice exhibit attenuated colitis compared with wild-type mice

immune system
decreased susceptibility to induced colitis ( J:173245 )
• dextran sodium sulfate (DSS)-treated mice housed with wild-type mice exhibit attenuated colitis compared with wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory