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Phenotypes Associated with This Genotype
Genotype
MGI:5014516
Allelic
Composition
Krastm4Tyj/Kras+
Ptentm1Hwu/Ptentm1Hwu
Genetic
Background
involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Krastm4Tyj mutation (4 available); any Kras mutation (30 available)
Ptentm1Hwu mutation (3 available); any Pten mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
tumorigenesis
• mutants injected with an adenoviral Cre into the right ovarian bursa to induce recombination develop ovarian cancer eight weeks after injection (J:161953)
• mutants injected with an adenoviral Cre into the right ovarian bursa to induce recombination develop ovarian cancer eight weeks after injection (J:161953)

Mouse Models of Human Disease
OMIM ID Ref(s)
Ovarian Cancer 167000 J:161953


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/26/2016
MGI 6.02
The Jackson Laboratory