Mouse Genome Informatics
tg
    Tg(MMTV-ERBB2*,-luc)6157Aami/0
FVB-Tg(MMTV-ERBB2*,-luc)6157Aami
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       

Tg(MMTV-ERBB2*,-luc)6157Aami/0 mice develop spontaneous mammary tumors

tumorigenesis
• 8 tumors at 18 weeks of age
• by 25 weeks, tumors metastasize to the lungs

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:172352