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Phenotypes Associated with This Genotype
Genotype
MGI:5009554
Allelic
Composition
Tg(Th-MYCN)41Waw/0
Trp53tm1Brd/Trp53+
Genetic
Background
involves: 129S7/SvEvBrd * BALB/c * C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Th-MYCN)41Waw mutation (1 available)
Trp53tm1Brd mutation (3 available); any Trp53 mutation (139 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mutants exhibit a tumor incidence similar to that of single hemizygous Tg(Th-MYCN)41Waw mice

neoplasm
• mutants exhibit a tumor incidence similar to that of single hemizygous Tg(Th-MYCN)41Waw mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Neuroblastoma, Susceptibility to 256700 J:41126


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory