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Phenotypes Associated with This Genotype
Genotype
MGI:5009550
Allelic
Composition
Tg(Th-MYCN)41Waw/Tg(Th-MYCN)41Waw
Genetic
Background
involves: BALB/c * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Th-MYCN)41Waw mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• homozygous mutants show increased incidence and decreased latency of neuroblastoma formation compared to hemizygous mice, with 100% of mice developing tumors at 4 months of age

neoplasm
• homozygous mutants show increased incidence and decreased latency of neuroblastoma formation compared to hemizygous mice, with 100% of mice developing tumors at 4 months of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
neuroblastoma DOID:769 OMIM:256700
OMIM:613013
OMIM:613015
OMIM:613016
J:41126


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory