mortality/aging
• median survival is 27 days following injection of PDGF and cre compared with 85 days for similarly treated Ptentm1Hwu homozygotes
|
neoplasm
• following injection of PDGF and cre, tumor growth is increased compared to in similarly treated Ptentm1Hwu homozygotes
|
• following injection of PDGF and cre, all mice develop glioblastoma composed of oligodendrocyte progenitor cells
|
nervous system
• following injection of PDGF and cre, all mice develop glioblastoma composed of oligodendrocyte progenitor cells
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
glioblastoma proneural subtype | DOID:0050804 | J:172585 |