Phenotypes Associated with This Genotype

Genotype
MGI:5007487

• Allelic Composition: Adora1^tm1Bbf/Adora1^tm1Bbf
• Genetic Background: B6.129P2-Adora1^tm1Bbf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

allodynia ( J:149872 )

• in the complete Freund's adjuvant model of chronic inflammatory pain or in the spared nerve injury model of neuropathic pain, mice injected with human ACPP exhibit increased mechanical allodynia compared with wild-type mice

decreased thermal nociceptive threshold ( J:149872 )

• in mice injected with human ACPP

• in mice injected with human ACPP in the complete Freund's adjuvant model of chronic inflammatory pain or in the spared nerve injury model of neuropathic pain