Mouse Genome Informatics
cx
    Boctm2Rsk/Boctm2Rsk
Cdontm1Rsk/Cdontm1Rsk

B6.129-Boctm2Rsk Cdontm1Rsk
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
nervous system
• display a range of holoprosencephalic phenotypes

craniofacial
N
• do not display cyclopia (J:171767)
• Background Sensitivity: unlike mice on a 129 background, mice on a C57BL/6 background display cleft lip
• proboscis like nose

vision/eye

limbs/digits/tail
N
• do not display digit patterning defects unlike Shh null mice (J:171767)

Mouse Models of Human Disease
OMIM IDRef(s)
Holoprosencephaly 236100 J:171767