Mouse Genome Informatics
hm
    Cryabtm1.1Ady/Cryabtm1.1Ady
involves: 129X1/SvJ * C57BL/6 * C57BL/6J
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
vision/eye
• in some mice, not bilateral
• overall in 84% of mice, beginning at 3 to 8 weeks and increasing in stage with age
• in some mice
• in some mice, not bilateral

muscle
• by 10 months, muscles exhibit dark basophilic fibers, internal nuclei, scattered necrosis, and fibrosis with alphabeta-crystallin inclusions unlike wild-type muscles

behavior/neurological

Mouse Models of Human Disease
OMIM IDRef(s)
Myopathy, Myofibrillar, 2; MFM2 608810 J:171679