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Phenotypes Associated with This Genotype
Genotype
MGI:4950720
Allelic
Composition		 Zfp830tm2.1Cota/Zfp830tm2.2Cota
Gt(ROSA)26Sortm2(cre/ERT2)Brn/?
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas * BALB/c * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm2(cre/ERT2)Brn mutation (1 available); any Gt(ROSA)26Sor mutation (942 available)
Zfp830tm2.1Cota mutation (0 available); any Zfp830 mutation (14 available)
Zfp830tm2.2Cota mutation (0 available); any Zfp830 mutation (14 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
decreased cell proliferation ( J:171647 )
• in tamoxifen-treated fibroblasts
early cellular replicative senescence ( J:171647 )
• proliferation of mouse embryonic fibroblasts is arrested 24 hours after tamoxifen-treatment unlike in control cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory