Phenotypes Associated with This Genotype

Genotype
MGI:4947651

• Allelic Composition: En1^tm1(Tnf)Fpit/En1^tm1(Tnf)Fpit
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

microgliosis ( J:170743 )

• in mice transfected with a cre-expressing adenovirus

astrocytosis ( J:170743 )

• in mice transfected with a cre-expressing adenovirus

abnormal dopaminergic neuron morphology ( J:170743 )

• mice treated with an adenovirus cre exhibit degeneration of the striatal dopaminergic terminals compared with wild-type mice

decreased neuron number ( J:170743 )

• in mice transfected with a cre-expressing adenovirus

neuron degeneration ( J:170743 )

• in mice transfected with a cre-expressing adenovirus

immune system

increased monocyte cell number ( J:170743 )

• mice transfected with a cre-expressing adenovirus exhibit chronic monocyte recruitment compared with wild-type mice

microgliosis ( J:170743 )

• in mice transfected with a cre-expressing adenovirus

hematopoietic system

increased monocyte cell number ( J:170743 )

• mice transfected with a cre-expressing adenovirus exhibit chronic monocyte recruitment compared with wild-type mice

microgliosis ( J:170743 )

• in mice transfected with a cre-expressing adenovirus