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Phenotypes Associated with This Genotype
Genotype
MGI:4946502
Allelic
Composition
Mtf2Gt(U3Betageo)1Ruiz/Mtf2Gt(U3Betageo)1Ruiz
Genetic
Background
involves: 129S2/SvPas
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mtf2Gt(U3Betageo)1Ruiz mutation (1 available); any Mtf2 mutation (314 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all mice die before weaning

skeleton
• shifted anteriorly
• mice exhibit ectopic ribs on the seventh cervical vertebrae unlike wild-type mice
• on the first cervical vertebrae
• mice exhibit posterior transformation at thoracolumbar and lumbosacral transitions unlike wild-type mice
• all mice exhibit T1 to T2 transformation
• all mice exhibit T7 to T8 transformation
• all mice exhibit T13 to L1 transformation
• all mice exhibit C1 to C2 transformation
• all mice exhibit C2 to C3 transformation
• all mice exhibit C5 to C6 transformation
• all mice exhibit C7 to T1 transformation
• all mice exhibit L5 or L6 to S1 transformation

cellular
• in mouse embryonic fibroblasts


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory