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Phenotypes Associated with This Genotype
Genotype
MGI:4941320
Allelic
Composition		 Rag2tm1.1Desi/Rag2tm1.1Desi
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag2tm1.1Desi mutation (0 available); any Rag2 mutation (117 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal immunoglobulin V(D)J recombination ( J:168974 )
• thymocytes accumulate recombination signal sequence breaks and increased frequency of aberrant V(D)J recombination compared with wild-type cells

immune system
abnormal immunoglobulin V(D)J recombination ( J:168974 )
• thymocytes accumulate recombination signal sequence breaks and increased frequency of aberrant V(D)J recombination compared with wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory