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Phenotypes Associated with This Genotype
Genotype
MGI:4940093
Allelic
Composition
Hand2tm1Dsr/Hand2tm2.1Dsr
Tg(Mef2c-cre)#Blk/0
Genetic
Background
involves: 129 * 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hand2tm1Dsr mutation (0 available); any Hand2 mutation (12 available)
Hand2tm2.1Dsr mutation (0 available); any Hand2 mutation (12 available)
Tg(Mef2c-cre)#Blk mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• immature truncus arteriosis
• mice lack the anlage of the tricuspid valve between the right atrium and ventricle unlike wild-type mice
• at E9.5 but not as severely as in Hand2tm1Dsr homozygotes

muscle


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory