About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4940051
Allelic
Composition
Atp7aMo-ms/Y
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atp7aMo-ms mutation (0 available); any Atp7a mutation (75 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

homeostasis/metabolism
• mice exhibit increased copper levels in the kidney but decreased copper levels in the brain and liver compared with wild-type mice

integument
• mice exhibit abnormal pigmentation and hair structure of the vibrissae compared with wild-type mice

liver/biliary system

mortality/aging
• mice die between 2 and 3 weeks of age

nervous system
• arcuate nucleus growth hormone-releasing hormone (GHRH) neurons exhibit morphological changes associated with apoptosis unlike in wild-type mice

pigmentation

cellular
• arcuate nucleus growth hormone-releasing hormone (GHRH) neurons exhibit morphological changes associated with apoptosis unlike in wild-type mice

Mouse Models of Human Disease
OMIM ID Ref(s)
Menkes Disease 309400 J:168658


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/17/2016
MGI 6.05
The Jackson Laboratory