Mouse Genome Informatics
ot
    Atp7aMo-ms/Y
Not Specified
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological

homeostasis/metabolism
• mice exhibit increased copper levels in the kidney but decreased copper levels in the brain and liver compared with wild-type mice

integument
• mice exhibit abnormal pigmentation and hair structure of the vibrissae compared with wild-type mice

liver/biliary system

mortality/aging
• mice die between 2 and 3 weeks of age

nervous system
• arcuate nucleus growth hormone-releasing hormone (GHRH) neurons exhibit morphological changes associated with apoptosis unlike in wild-type mice

pigmentation

cellular
• arcuate nucleus growth hormone-releasing hormone (GHRH) neurons exhibit morphological changes associated with apoptosis unlike in wild-type mice

Mouse Models of Human Disease
OMIM IDRef(s)
Menkes Disease 309400 J:168658