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Phenotypes Associated with This Genotype
Genotype
MGI:4889081
Allelic
Composition		 Relnrl/Relnrl
Tg(Mbp-MAPT/lacZ)#aCaw/Tg(Mbp-MAPT/lacZ)#aCaw
Genetic
Background		 involves: BALB/c * C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Relnrl mutation (3 available); any Reln mutation (209 available)
Tg(Mbp-MAPT/lacZ)#aCaw mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon extension ( J:168258 )
• thalamocortical axons fail to extend beneath the cortical plate and grow obliquely across it unlike in wild-type mice

cellular
abnormal axon extension ( J:168258 )
• thalamocortical axons fail to extend beneath the cortical plate and grow obliquely across it unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory