Phenotypes for Runx2 Zfp521 MGI:4887971 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Runx2^tm1Mjo/Runx2⁺ Zfp521^tm2Ngc/Zfp521⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Runx2^tm1Mjo mutation (0 available); any Runx2 mutation (42 available)
Zfp521^tm2Ngc mutation (0 available); any Zfp521 mutation (51 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

decreased hyoid bone size ( J:167992 )

• the mineralized midpoint of the hyoid bone is decreased in length compared to in wild-type mice

• however, mineralization occurs unlike in Runx2^tm1Mjo heterozygotes

skeleton

decreased hyoid bone size ( J:167992 )

• the mineralized midpoint of the hyoid bone is decreased in length compared to in wild-type mice

• however, mineralization occurs unlike in Runx2^tm1Mjo heterozygotes

clavicle hypoplasia ( J:167992 )

• clavicle is smaller than in wild-type mice but not as severely reduced as in Runx2^tm1Mjo heterozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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