Phenotypes for Pnpt1 MGI:4882059 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Pnpt1^tm1.1Teit/Pnpt1^tm1.1Teit
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pnpt1^tm1.1Teit mutation (0 available); any Pnpt1 mutation (40 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:167932 )

cellular

abnormal mitochondrial physiology ( J:167932 )

• mitochondria of mouse embryonic fibroblasts fail to exhibit import of RNase P RNA unlike wild-type cells

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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