Mouse Genome Informatics
hm
    Lmnatm8Lgf/Lmnatm8Lgf
involves: 129P2/OlaHsd
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• mice exhibit normal survival

cardiovascular system
• at 12 months, mice exhibit slightly reduced left ventricular posterior wall thickness compared to in wild-type mice

cellular
• misshapen with blebs in fibroblasts and rarely in liver cells

adipose tissue
N
• mice exhibit normal body fat

growth/size/body
N
• mice exhibit normal body weight curves

skeleton
N
• mice exhibit normal bone density

muscle

Mouse Models of Human Disease
OMIM IDRef(s)
NOT Hutchinson-Gilford Progeria Syndrome; HGPS 176670 J:167229