Analysis Tools
mortality/aging
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• mice undergo resorption as early as E8.5
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nervous system
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• mice exhibit disorganized neuronal growth in the forebrain, cerebellum, and midbrain with formation of irregular neuronal rosettes and folds unlike in wild-type mice
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• at E13.5, mice exhibit abnormal brain development that likely results in lethality unlike in wild-type mice
• mice exhibit disorganized neuronal growth in the forebrain, cerebellum, and midbrain with formation of irregular neuronal rosettes and folds unlike in wild-type mice
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• underdeveloped and disorganized at E13.5
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• underdeveloped at E13.5
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• underdeveloped at E13.5
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• disorganized at E13.5
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• at E13.5, the mesencephalic vesicle is underdeveloped compared to in wild-type mice
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• disorganized at E13.5
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growth/size/body
embryo
cellular
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• mice exhibit disorganized neuronal growth in the forebrain, cerebellum, and midbrain with formation of irregular neuronal rosettes and folds unlike in wild-type mice
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