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Phenotypes Associated with This Genotype
Genotype
MGI:4867886
Allelic
Composition
Itm2btm3.1Ldad/Itm2btm3.1Ldad
Genetic
Background
B6.129-Itm2btm3.1Ldad
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2btm3.1Ldad mutation (0 available); any Itm2b mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice spend the same time exploring a novel and familiar object introduced 24 hours prior unlike wild-type mice
• mice exhibit impaired spatial working memory compared with wild-type mice

nervous system
N
• mice do not exhibit familial British dementia-related neuropathy

Mouse Models of Human Disease
OMIM ID Ref(s)
Cerebral Amyloid Angiopathy, Itm2b-Related, 1 176500 J:166696


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory