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Phenotypes Associated with This Genotype
Genotype
MGI:4831171
Allelic
Composition
Ccr2tm1Ifc/Ccr2+
Tg(APPSWE)2576Kha/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ccr2tm1Ifc mutation (1 available); any Ccr2 mutation (43 available)
Tg(APPSWE)2576Kha mutation (5 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• by 130 days, 60% of mice are dead compared with 30% of mice expressing Tg(APPSWE)2576Kha, 1% of wild-type mice, and 3% of Ccr2tm1Ifc homozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory