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Phenotypes Associated with This Genotype
Genotype
MGI:4822143
Allelic
Composition
avc2/avc2
Genetic
Background
involves: C57BL/6J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
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See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging

cardiovascular system
• each mutant mouse displayed an incomplete AVSD (an atrial septal defect of the primum type)
• Background Sensitivity: the phenotype is incompletely penetrant was lost after repeated outcrossing to FVB; however, the phenotype was re-established after a two-generation backcross to a C57BL/6-A/J chromosome 15 chromosome substitution strain (C57BL/6J-Chr15A/NaJ)

limbs/digits/tail
• observed on all limbs

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
atrial heart septal defect 1 DOID:0110106 OMIM:108800
J:163196


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/10/2017
MGI 6.10
The Jackson Laboratory