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Phenotypes Associated with This Genotype
Genotype
MGI:4820822
Allelic
Composition
Tg(Igh-Mir29a,-Mir29b-1,-hrGFP)#Cro/0
Tg(Igh-V186.2-TCL1A)3Cro/0
Genetic
Background
involves: C3H * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• 3-fold increases in spleen weight compared to Tg(Igh-V186.2-TCL1A)3Cro mice alone

hematopoietic system
• 3-fold increases in spleen weight compared to Tg(Igh-V186.2-TCL1A)3Cro mice alone
• increased number of CD5+ B cells in spleen

immune system
• 3-fold increases in spleen weight compared to Tg(Igh-V186.2-TCL1A)3Cro mice alone
• increased number of CD5+ B cells in spleen

neoplasm
• a significant increased number of CD5+CD19+ and CD5+IgM+ B-cell populations compared with Tg(Igh-V186.2-TCL1A)3Cro mice alone


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory