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Phenotypes Associated with This Genotype
Genotype
MGI:4818991
Allelic
Composition		 Tg(Prnp-APP*)3Hmor/0
Genetic
Background		 B6.Cg-Tg(Prnp-APP*)3Hmor
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
reduced long-term potentiation ( J:123688 , J:159623 )
• mice exhibit decreased long term potentiation compared with wild-type mice that is greater than in Tg(Prnp-APP)#Hmor mice (not statistically significant) (J:159623)
decreased paired-pulse facilitation ( J:123688 , J:159623 )
• mice exhibit decreased paired-pulse facilitation compared with wild-type mice that is greater than in Tg(Prnp-APP)#Hmor mice (not statistically significant) (J:159623)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory