Mouse Genome Informatics
hm
    Pdgfratm2Sor/Pdgfratm2Sor
involves: 129S4/SvJaeSor * C57BL/6
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging

muscle
• at E12, some surviving mice exhibit little to no diaphragm formation unlike wild-type mice
• at E12, some surviving mice exhibit delayed closure of bilateral posterior pleuroperitoneal folds unlike wild-type mice
• 2 of 7 mice exhibit open posterior pleuroperitoneal folds with variable herniation of the stomach into the thorax unlike wild-type mice

respiratory system

cardiovascular system

Mouse Models of Human Disease
OMIM IDRef(s)
Diaphragmatic Hernia, Congenital 142340 J:160875