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Phenotypes Associated with This Genotype
Genotype
MGI:4462170
Allelic
Composition		 Nrp1tm1Ddg/Nrp1tm1Ddg
Genetic
Background		 involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrp1tm1Ddg mutation (2 available); any Nrp1 mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal T cell physiology ( J:161856 )
• defective T-cell priming by antigen
abnormal dendritic cell physiology ( J:161856 )
• impaired dendritic cell migration

vision/eye
vision/eye phenotype ( J:172268 )
N
• mice exhibit normal retinal stratification

hematopoietic system
abnormal T cell physiology ( J:161856 )
• defective T-cell priming by antigen

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory