Analysis Tools
reproductive system
| N |
• female mice exhibit normal fertility
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azoospermia
(
J:161124
)
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• mice lack elongating spermatids unlike wild-type mice
• epididymides lack mature sperm unlike wild-type mice
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• mice lack elongating spermatids unlike wild-type mice
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• mice exhibit many round, pachytene-like spermatocytes with degenerating nuclei unlike wild-type mice
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• beginning at P15
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• at P19 and P24
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• marker staining indicates that the synaptonemal complex does not assemble correctly in spermatocytes unlike in wild-type cells
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• before the pachytene stage
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• primary spermatocytes exhibit activation of long terminal repeats (LTRs) and LINE-1 retrotransposons unlike in wild-type cells
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• beginning at P15, some tubules show massive TUNEL staining of the most mature spermatocytes
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endocrine/exocrine glands
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• beginning at P15
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• at P19 and P24
|
cellular
azoospermia
(
J:161124
)
|
|
• mice lack elongating spermatids unlike wild-type mice
• epididymides lack mature sperm unlike wild-type mice
|
|
|
• mice lack elongating spermatids unlike wild-type mice
|
|
|
• mice exhibit many round, pachytene-like spermatocytes with degenerating nuclei unlike wild-type mice
|
|
|
• beginning at P15, some tubules show massive TUNEL staining of the most mature spermatocytes
|
