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Phenotypes Associated with This Genotype
Genotype
MGI:4455028
Allelic
Composition
RhoTvrm1/Rho+
Rpe65rd12/Rpe65rd12
Genetic
Background
B6.Cg-Rpe65rd12 RhoTvrm1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
RhoTvrm1 mutation (1 available); any Rho mutation (29 available)
Rpe65rd12 mutation (1 available); any Rpe65 mutation (24 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• photoreceptor degeneration without exposure to bright light
• the peripheral retina also shows cell loss but is better preserved than the central retina
• at 4 weeks of age, retinas have only 5 rows of cell bodies remaining in the central outer nuclear layer

nervous system
• photoreceptor degeneration without exposure to bright light
• the peripheral retina also shows cell loss but is better preserved than the central retina

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
retinitis pigmentosa DOID:10584 OMIM:268000
J:159523


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/05/2017
MGI 6.11
The Jackson Laboratory