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Phenotypes Associated with This Genotype
Genotype
MGI:4442809
Allelic
Composition		 Ugcgtm1Rlp/Ugcgtm4Rlp
Tg(Nes-cre)1Kln/0
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nes-cre)1Kln mutation (4 available)
Ugcgtm1Rlp mutation (0 available); any Ugcg mutation (86 available)
Ugcgtm4Rlp mutation (1 available); any Ugcg mutation (86 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
limb grasping ( J:103415 )
• at 6 months
abnormal gait ( J:103415 )
• aged mice exhibit a labored gait unlike wild-type mice

nervous system
Purkinje cell degeneration ( J:103415 )
• severe at 9 months
• increases with age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory